Transition-metal and organo-catalysis in organic synthesis: Metal-catalyzed reactions
Akshay R Yadav
Transition metal catalyzed reactions are fundamental for the synthesis of organic molecules. Homogeneous catalysis offers a very fast approach to new organic compounds, which are then tested for their desired properties, and thus helps to solve current health, environmental, energy storage and other problems. The chemical community has witnessed the fruitful growth of the powerful strategy of transition metal catalysis. Demonstrating the possibility of overcoming any inhibition or quenching by concomitantly merging simple amine catalysts, providing nucleophilic coupled with transition metal activated electrophilic intermediate. Novel strategies adopting the stereodivergent preparation of a wide range of important compounds with multiple stereocenters and with diversified functionalities, which additionally expands the chemical space. We believe this strategy will continue emerging into new innovative reactions allowing the coupling of more challenging components with indefinite chemical transformations.
Akshay R Yadav. Transition-metal and organo-catalysis in organic synthesis: Metal-catalyzed reactions. International Journal of Pharmacy and Pharmaceutical Science, Volume 2, Issue 1, 2020, Pages 06-09