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International Journal of Pharmacy and Pharmaceutical Science

Vol. 3, Issue 1, Part A (2021)

Formulation and evaluation of anti-bacterial herbal gels of Psidium guajava, Murraya koenigii, and Musa acuminata leaves extract

Author(s):

Subodh U Bansod, Vaishali H Bawankar, Sanjay S Patle, Shivkanya S Jojar and Sakshi S Talan

Abstract:

Herbal medicine has become an item of global importance both medicinal and economical. Herbal remedies are getting increasing patient compliance as they are devoid of typical side effects of allopathic medicines. The present research has been undertaken with the aim to formulate and evaluate the herbal gels containing Murraya koenigii (Curry leaves), Psidium guajava (Guava leaves), Musa acuminata (Banana leaves) plant leaf extract. The gel formulations were prepared by using Carbapol 940, Murraya koenigii, Psidium guajava, Musa acuminata leaf extract, propylene glycol, methyl paraben, propyl paraben, glycerine and required amount of distilled water. The skin pH (6.8-7) was maintained by drop wise addition of Tri-ethanolamine. The physical parameters of formulated gels like colour, homogeneity, pH, viscosity and spreadibility were evaluated. The gels were evaluated for antibacterial efficiency by agar diffusion method against some bacterial agents. The herbal gels showed that formulations containing Murraya koenigii, Psidium guajava, Musa acuminata leaves extract have better antibacterial activity. 
Musa acuminata, commonly known as banana plant is vastly being consumed across the world. It is known for many antimicrobial activities and reports show that phenolic compounds mainly contribute to this trait. Considering these advantages an herbal gel containing 4% extract obtained from plant leaves was prepared. Extraction of phenolic compound from leaves was carried out using suitable solvent. The phenolic recovery from acetone extract was showing good antimicrobial activity. The physiochemical parameters of formulations (pH, viscosity, Spread ability and homogeneity) were determined. The herbal gel showed that formulation containing Musa acuminata leaves extract have better antimicrobial activity. The antimicrobial activity was carried out against E.coli and Candida albicans.
Nature has endowed Guava with many nutritional and medicinal properties. The fruits are 4-12 cm long with round or oval shape depending on the species (red, strawberry, and off-white). The tree, which belongs to the family, Myrtaceae is chiefly grown in countries with tropical and subtropical climate. The pink variety of guava (when dissected) has the maximum medicinal values. Fruits as well as leaves has many health benefits viz, antidiarrheal, antihypertensive, antilipedemic, anticancer etc. 
 

Pages: 37-43  |  48 Views  14 Downloads

How to cite this article:
Subodh U Bansod, Vaishali H Bawankar, Sanjay S Patle, Shivkanya S Jojar and Sakshi S Talan. Formulation and evaluation of anti-bacterial herbal gels of Psidium guajava, Murraya koenigii, and Musa acuminata leaves extract. Int. J. Pharm. Pharm. Sci. 2021;3(1):37-43. DOI: 10.33545/26647222.2021.v3.i1a.67