Vol. 5, Issue 2, Part A (2023)

Anti-dandruff hair gels were prepared and evaluated as part of a study. Hair gels' physiochemical properties have been established. Hair gel in-vitro drug release profiles were carried out. It was discovered that prepared hair gels released medication based on the In-vitro drug release profile. The Climbazole formulation F5 demonstrated an excellent release profile when compared to other formulations, and it displayed the same zone of inhibition as the pure drug. F5 was therefore thought to be an effective composition for treating dandruff. In conclusion, the contact time in terms of hours in the affected area might be improved for the hair gels by using regularly used gelling agents. To establish stable gel products, however, long-term stability tests are required. To confirm its effectiveness in the treatment of dandruff, more clinical trials are required.