Vol. 6, Issue 1, Part B (2024)

A bacteria-related infection that can affect multiple organs and spread throughout the body is typhoid fever. It can be lethal and result in major complications. It is brought on by the Salmonella typhi bacteria, which is related to the germs that cause food poisoning. Enteric fever is another name for typhoid fever. It is a potentially multisystemic condition that has posed a challenge to public health, particularly in developing nations. Salmonella typhi and Salmonella paratyphi are the causes. The bacillus that was thought to be the source of typhoid fever was initially described by Karl Joseph Eberth in 1880. Pathologist Georg Gaffky identified the bacillus Eberthella typhi, which is now known as Salmonella typhosus (also known as Bacillus typhosus), four years after the pathologist first established this connection. Typhoid fever is quite frequent in India, with varying rates of transmission throughout the country and a higher incidence in urban areas. In this review study, we discuss the pathophysiology, epidemiology, therapy, diagnosis, and aetiology of typhoid.