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International Journal of Pharmacy and Pharmaceutical Science

Vol. 7, Issue 1, Part A (2025)

Emerging trends in osmotic pumps: A revolution in drug delivery systems

Author(s):

G Sai Bhavija, P Venkata Anudeep and Y Prapurna Chandra

Abstract:

The field of drug delivery systems has witnessed significant advancements, with osmotic pumps emerging as a reliable solution for controlled drug administration in both humans and animals. These systems utilize the principle of osmosis to regulate the release of therapeutic agents, ensuring a consistent and predictable drug delivery rate. Unlike traditional dosage forms, osmotic pumps operate independently of the gastrointestinal environment, offering advantages such as improved drug stability and reduced side effects. Drug release in osmotic systems is influenced by factors like the solubility and osmotic pressure of the core components, the size of the delivery orifice, and the properties of the rate-controlling membrane. These pumps address challenges associated with immediate-release formulations, such as fluctuations in plasma drug levels, by maintaining steady therapeutic concentrations over extended periods. This controlled release mechanism enhances patient compliance by minimizing dosing frequency and ensuring sustained efficacy. Osmotic pumps consist of a drug-containing core, osmotic agents, and a semipermeable membrane that allows water to enter, generating pressure to expel the drug through a precision-engineered orifice. These systems are compact, energy-efficient, and suitable for various applications, including long-term treatments. By bypassing limitations like gastrointestinal transit time and first-pass metabolism, osmotic pumps represent a promising advancement in drug delivery technology, offering consistent performance and improved therapeutic outcomes.

Pages: 33-38  |  74 Views  27 Downloads


International Journal of Pharmacy and Pharmaceutical Science
How to cite this article:
G Sai Bhavija, P Venkata Anudeep and Y Prapurna Chandra. Emerging trends in osmotic pumps: A revolution in drug delivery systems. Int. J. Pharm. Pharm. Sci. 2025;7(1):33-38. DOI: 10.33545/26647222.2025.v7.i1a.148