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International Journal of Pharmacy and Pharmaceutical Science
Peer Reviewed Journal

Vol. 7, Issue 2, Part A (2025)

Phytochemical standardization of Cassia fistula (Pods) and evaluation of diuretic activity

Author(s):

Ragini Singh, Shilpi Mishra, Ashish Mishra, Shivraj Singh Bhadauriya and Surina Yadav

Abstract:

This study aimed to evaluate the diuretic activity of Cassia fistula & the present study was carried out to investigate the diuretic activity of ethanol and aqueous extract of the pods of cassia fistula (CFEE), (CFAE) to make a herbal formulation & were administered to experiment wistar rats orally at the dose level of 100 mg/kg and compared with standard drug furosemide (20 mg/kg). The Lipschistz method used in rats for the experiment purpose. The Cassia fistula formulation showed a market level of increase in urine volume and electrolytes like Na+, K+, and Cl- ion concentration. The moderate diuretic effects was observed and significant diuretic effects from Cassia fistula formulation. Cassia fistula formulation (100 mg/kg) showed more diuretic effect than standard. This might be the first formal report on diuretic activity of cassia fistula plant.

 

Pages: 52-58  |  680 Views  234 Downloads


International Journal of Pharmacy and Pharmaceutical Science
How to cite this article:
Ragini Singh, Shilpi Mishra, Ashish Mishra, Shivraj Singh Bhadauriya and Surina Yadav. Phytochemical standardization of Cassia fistula (Pods) and evaluation of diuretic activity. Int. J. Pharm. Pharm. Sci. 2025;7(2):52-58. DOI: 10.33545/26647222.2025.v7.i2a.196