Vol. 8, Issue 1, Part A (2026)

Lipid based drug delivery system {LBDDS} are an emerging technology designed to address challenges like the solubility and bioavailability of poorly water soluble drugs. This review article focuses on novel lipid based formulations, including emulsions, vesicular systems, and lipid particulate systems, as well as their applications in pharmaceutical drug delivery.
The paper discusses the principle objectives of formulating lipid based drugs, which is to enhance their bioavailability. It covers various aspects of LBDDS, including formulations approaches, characterisation methods, stability considerations, and regulatory aspects.
The lipid based for formulations can be tailored to meet a wide range of product requirements and are commercially viable for formulating pharmaceuticals for topical, oral, pulmonary, or parenteral delivery. The review also notes that lipid based formulations have shown the ability to reduce toxicity of various drugs by changing their biodistribution away from sensitive organs.