Vol. 6, Issue 1, Part A (2024)

The word "phyto" has to do with plants and the word "somes" has to do with cellular structures. Phytosomes are better at getting through lipid-rich bio membranes and into the circulatory system, they tend to have a higher bioavailability than simple plant extracts. As a hepatoprotection, phospholipids used in the phytosome mixture have been shown to be effective as a therapy. The main way that phospholipids and the active substance work together is through the establishment of hydrogen bonds among the polar components of the phytoconstituent and the polar parts of the phospholipids. The phytosome structure can be thought of as a cell, which protects the bioactive parts of the plant extract from being broken down by digestive juices and intestinal bacteria. Phytosomes are a type of a vesicular delivery system based on lipids that solves the problem of the low absorption of hydrophilic phytoconstituents. Preparations made from plants have been used to keep people healthy since ancient times. There are several good things about using herbal drugs. These benefits include making the drug more soluble and bioavailable, protecting it from toxicity, increasing its pharmacological activity, making it more stable, spreading it out more in tissue macrophages, giving it for a longer time and keeping it from breaking down physically or chemically. Because phytosomes are more lipid-soluble, they are easier to absorb through the skin and the digestive system. This means that they can pass through cellular membranes, which makes them more bioavailable at the site of action.